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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: OPLAH All Species: 28.18
Human Site: S481 Identified Species: 56.36
UniProt: O14841 Number Species: 11
    Phosphosite Substitution
    Charge Score: -0.18
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O14841 NP_060040.1 1288 137457 S481 Q A R G H D P S A H V L A C F
Chimpanzee Pan troglodytes XP_528261 1212 130154 L472 M C R P I R A L T Q A R G H D
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_539206 1379 147579 S578 Q A R G H D P S A H V L A C F
Cat Felis silvestris
Mouse Mus musculus Q8K010 1288 137593 S481 Q A R G H D P S A H V L A C F
Rat Rattus norvegicus P97608 1288 137702 S481 Q A R G H D P S A H V L A C F
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001521030 1300 139318 S492 Q A K G H D T S Q H I L A C F
Chicken Gallus gallus
Frog Xenopus laevis
Zebra Danio Brachydanio rerio
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster NP_611675 1294 139594 A481 Q S R G L D T A N H V L S C F
Honey Bee Apis mellifera XP_001121487 1287 139635 S482 Q A K G Y D T S R H V L A C F
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_794494 1307 142838 S490 Q A K G H D T S H H V L A C F
Poplar Tree Populus trichocarpa XP_002305860 1269 137853 R489 E M K G H E T R N H A L A C F
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9FIZ7 1266 137512 K485 E M K G H E T K N H A L A C F
Baker's Yeast Sacchar. cerevisiae P28273 1286 140409 S486 E A K G H V V S Q H R L V S F
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 92.5 N.A. 69.4 N.A. 92.5 93.9 N.A. 80.2 N.A. N.A. N.A. N.A. 61.2 65 N.A. 64.1
Protein Similarity: 100 93.1 N.A. 74 N.A. 95.6 96.1 N.A. 87.2 N.A. N.A. N.A. N.A. 74.5 76.9 N.A. 76.1
P-Site Identity: 100 6.6 N.A. 100 N.A. 100 100 N.A. 73.3 N.A. N.A. N.A. N.A. 60 73.3 N.A. 80
P-Site Similarity: 100 6.6 N.A. 100 N.A. 100 100 N.A. 86.6 N.A. N.A. N.A. N.A. 80 86.6 N.A. 86.6
Percent
Protein Identity: 57.2 N.A. N.A. 56.8 49 N.A.
Protein Similarity: 70.9 N.A. N.A. 71.2 66 N.A.
P-Site Identity: 46.6 N.A. N.A. 46.6 46.6 N.A.
P-Site Similarity: 66.6 N.A. N.A. 66.6 60 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 67 0 0 0 0 9 9 34 0 25 0 75 0 0 % A
% Cys: 0 9 0 0 0 0 0 0 0 0 0 0 0 84 0 % C
% Asp: 0 0 0 0 0 67 0 0 0 0 0 0 0 0 9 % D
% Glu: 25 0 0 0 0 17 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 92 % F
% Gly: 0 0 0 92 0 0 0 0 0 0 0 0 9 0 0 % G
% His: 0 0 0 0 75 0 0 0 9 92 0 0 0 9 0 % H
% Ile: 0 0 0 0 9 0 0 0 0 0 9 0 0 0 0 % I
% Lys: 0 0 50 0 0 0 0 9 0 0 0 0 0 0 0 % K
% Leu: 0 0 0 0 9 0 0 9 0 0 0 92 0 0 0 % L
% Met: 9 17 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 25 0 0 0 0 0 0 % N
% Pro: 0 0 0 9 0 0 34 0 0 0 0 0 0 0 0 % P
% Gln: 67 0 0 0 0 0 0 0 17 9 0 0 0 0 0 % Q
% Arg: 0 0 50 0 0 9 0 9 9 0 9 9 0 0 0 % R
% Ser: 0 9 0 0 0 0 0 67 0 0 0 0 9 9 0 % S
% Thr: 0 0 0 0 0 0 50 0 9 0 0 0 0 0 0 % T
% Val: 0 0 0 0 0 9 9 0 0 0 59 0 9 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 9 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _